CNXII Hypoglossal Nerve

Authors
Affiliations

Nathaniel Yomogida, B.S., SPT

Doctor of Physical Therapy

B.S. in Kinesiology

Chloë Kerstein, B.S., SPT

Doctor of Physical Therapy

B.A. in Neuroscience

Dysfunction

Syndromes involving CN9-12 (CN IX-XII) from Table 13-11
Syndrome (Eponym) Nerves Affected Location of Lesion
Collet-Sicard CN IX, X, XI, XII1 Retroparotid space usually
Lesion may be intracranial or extracranial1
Villaret CN IX, X, XI, XII
Plus the sympathetic chain
CN VII is occassionally involved1		 Retroparotid or retropharyngeal space1
Jackson CN IX, X, & XI1 May be intraparenchymal (medulla);
Usually intracranial before nerve fibers leave the skull1
Tapia CN X & XII
(CNXI and the sympathetic chain are occassionally involved)1		 Usually high in the neck1
Garcin (hemibase syndrome) All Cranial Nerves on one side
(often incomplete)1		 Often infiltrative;
Arising from base of skull (especially nasopharyngeal carcinoma)1

References

1.
Brazis PW, Masdeu JC, Biller J. Localization in Clinical Neurology. 8th ed. Wolters Kluwer Health; 2022.

Citation

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